{"id":21475,"date":"2011-11-09T15:34:30","date_gmt":"2011-11-09T18:34:30","guid":{"rendered":"http:\/\/www.inclusive.org.br\/?p=21475"},"modified":"2011-11-09T15:34:30","modified_gmt":"2011-11-09T18:34:30","slug":"novas-sindromes-geneticas","status":"publish","type":"post","link":"https:\/\/inclusivenews.com.br\/?p=21475","title":{"rendered":"Novas s\u00edndromes gen\u00e9ticas"},"content":{"rendered":"
\"\"<\/a>
<\/figcaption><\/figure>\n

Por Elton Alisson
\nAg\u00eancia FAPESP<\/strong><\/p>\n

Nos \u00faltimos 14 anos, um novo grupo de doen\u00e7as heredit\u00e1rias raras come\u00e7ou a ser identificado em diferentes partes do mundo. S\u00e3o causadas por defici\u00eancias gen\u00e9ticas da imunidade inata e, se n\u00e3o forem diagnosticadas precocemente e tratadas de forma adequada, podem levar a complica\u00e7\u00f5es graves de sa\u00fade.<\/p>\n

Para estudar a preval\u00eancia e melhorar a capacidade de diagn\u00f3stico no Brasil dessas novas doen\u00e7as, chamadas s\u00edndromes autoinflamat\u00f3rias heredit\u00e1rias, um grupo de pesquisadores de diferentes institui\u00e7\u00f5es no pa\u00eds e nos Estados Unidos realizou, nos \u00faltimos tr\u00eas anos, um estudo de abrang\u00eancia nacional.<\/p>\n

Os resultados da pesquisa ser\u00e3o apresentados no Encontro Cient\u00edfico Anual do Col\u00e9gio Americano de Reumatologia (ACR, na sigla em ingl\u00eas), que ocorre at\u00e9 9 de novembro em Chicago, nos Estados Unidos.<\/p>\n

Realizado com apoio da FAPESP e das sociedades brasileiras de Pediatria e Reumatologia, o projeto<\/a><\/strong> teve a participa\u00e7\u00e3o de pesquisadores das universidades de S\u00e3o Paulo (USP), Estadual de Campinas, do Estado do Rio de Janeiro, das federais de S\u00e3o Paulo, Rio de Janeiro, Goi\u00e1s e Pernambuco e do Instituto Nacional de Alergia e Doen\u00e7as Infecciosas (NIAID), nos Estados Unidos.<\/p>\n

Por meio da pesquisa foram identificados 103 pacientes no Brasil, entre adultos e crian\u00e7as, com suspeita cl\u00ednica de serem portadores de uma das cinco s\u00edndromes inflamat\u00f3rias mais prevalentes no mundo: febre familiar do Mediterr\u00e2neo; criopirinopatias; artrite granulomatosa pedi\u00e1trica; hiperimunoglobulinemia D ou defici\u00eancia de mevalatoquinase; e s\u00edndrome peri\u00f3dica associada ao receptor do fator de necrose tumoral.<\/p>\n

Entre esses 103 pacientes, os pesquisadores identificaram e sequenciaram os genes relacionados a essas cinco s\u00edndromes em cerca de um ter\u00e7o deles.<\/p>\n

\u201cComo essas s\u00edndromes s\u00e3o muito parecidas \u2013 os sintomas s\u00e3o iguais e tamb\u00e9m podem existir outras novas doen\u00e7as semelhantes a elas \u2013 n\u00e3o foram identificados e sequenciados os genes das doen\u00e7as apresentadas por cerca de dois ter\u00e7os dos pacientes\u201d, disse Clovis Artur Almeida da Silva, professor da USP e coordenador do projeto, \u00e0 Ag\u00eancia FAPESP.<\/strong><\/p>\n

O objetivo agora \u00e9 dar continuidade \u00e0 identifica\u00e7\u00e3o e ao sequenciamento gen\u00e9tico desses pacientes, de modo a aprimorar a capacidade de diagn\u00f3stico dessas doen\u00e7as, para as quais est\u00e3o surgindo novos tratamentos.<\/p>\n

\u201cAinda n\u00e3o temos condi\u00e7\u00f5es de avaliar todos os pacientes portadores dessas doen\u00e7as, cujo tratamento \u00e9 espec\u00edfico para cada uma delas\u201d, afirmou.<\/p>\n

Caracterizadas por febre peri\u00f3dica e sintomas inflamat\u00f3rios sist\u00eamicos recorrentes, como artrite, dores abdominais, manchas na pele e inflama\u00e7\u00f5es oculares e do sistema nervoso central, entre outras, essas doen\u00e7as est\u00e3o sendo diagnosticadas em todo o mundo. Entretanto, j\u00e1 se sabe que afetam, principalmente, popula\u00e7\u00f5es do Mediterr\u00e2neo, como turcos, arm\u00eanios, judeus sefarditas (origin\u00e1rios de pa\u00edses ib\u00e9ricos) e \u00e1rabes, devido \u00e0 consanguinidade.<\/p>\n

\u201cS\u00e3o muito comuns os casamentos entre parentes nessas popula\u00e7\u00f5es. Como essas doen\u00e7as s\u00e3o heredit\u00e1rias e t\u00eam heran\u00e7as distintas, elas acabam acometendo um maior n\u00famero de pessoas nessas regi\u00f5es geogr\u00e1ficas\u201d, explicou Silva. Em algumas dessas regi\u00f5es, a preval\u00eancia de casos das doen\u00e7as varia de 1 para 200 a de 1 para 1.000 pessoas.<\/p>\n

DIRA<\/p>\n

No Brasil, ainda n\u00e3o se sabe exatamente qual a preval\u00eancia. \u201cApresentamos os resultados da pesquisa inicial no Congresso Brasileiro de Reumatologia Pedi\u00e1trica, que ocorreu no in\u00edcio de outubro em Salvador, e diversos pesquisadores t\u00eam nos enviado e-mails relatando que t\u00eam pacientes com sintomas parecidos com os dessas doen\u00e7as. \u00c0 medida que elas forem mais divulgadas no Brasil, surgir\u00e3o outros novos casos\u201d, disse.<\/p>\n

Para identificar casos das doen\u00e7as no Brasil, foram coletadas amostras de soro sangu\u00edneo de casos cl\u00ednicos, com maior predomin\u00e2ncia da regi\u00e3o Sudeste e a aus\u00eancia da regi\u00e3o Norte, onde n\u00e3o foi registrado nenhum paciente portador dessas doen\u00e7as.<\/p>\n

Entre os casos cl\u00ednicos levantados, foram identificados os de duas crian\u00e7as que apresentavam inflama\u00e7\u00f5es cut\u00e2neas, como psor\u00edase e manchas na pele, e osteomielite n\u00e3o infecciosa.<\/p>\n

Os pesquisadores estimavam que as crian\u00e7as eram portadoras de uma s\u00edndrome inflamat\u00f3ria j\u00e1 identificada. Ao enviar os genes delas para serem sequenciados por outro pesquisador no Qatar, nos Emirados \u00c1rabes, o grupo brasileiro descobriu uma nova s\u00edndrome na popula\u00e7\u00e3o brasileira, batizada de DIRA.<\/p>\n

A descoberta ser\u00e1 publicada em uma das pr\u00f3ximas edi\u00e7\u00f5es da revista Arthritis & Rheumatism<\/em>, do Col\u00e9gio Americano de Reumatologia.<\/p>\n

Fonte: Ag\u00eancia FAPESP<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Nos \u00faltimos 14 anos, um novo grupo de doen\u00e7as heredit\u00e1rias raras come\u00e7ou a ser identificado em diferentes partes do mundo. S\u00e3o causadas por defici\u00eancias gen\u00e9ticas da imunidade inata e, se n\u00e3o forem diagnosticadas precocemente e tratadas de forma adequada, podem levar a complica\u00e7\u00f5es graves de sa\u00fade. Da Ag\u00eancia FAPESP.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-container-style":"default","site-container-layout":"default","site-sidebar-layout":"default","disable-article-header":"default","disable-site-header":"default","disable-site-footer":"default","disable-content-area-spacing":"default","footnotes":""},"categories":[4,37],"tags":[],"class_list":["post-21475","post","type-post","status-publish","format-standard","hentry","category-noticias","category-saude"],"yoast_head":"\nNovas s\u00edndromes gen\u00e9ticas -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/inclusivenews.com.br\/?p=21475\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Novas s\u00edndromes gen\u00e9ticas -\" \/>\n<meta property=\"og:description\" content=\"Nos \u00faltimos 14 anos, um novo grupo de doen\u00e7as heredit\u00e1rias raras come\u00e7ou a ser identificado em diferentes partes do mundo. S\u00e3o causadas por defici\u00eancias gen\u00e9ticas da imunidade inata e, se n\u00e3o forem diagnosticadas precocemente e tratadas de forma adequada, podem levar a complica\u00e7\u00f5es graves de sa\u00fade. Da Ag\u00eancia FAPESP.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/inclusivenews.com.br\/?p=21475\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/agenciainclusive\/\" \/>\n<meta property=\"article:published_time\" content=\"2011-11-09T18:34:30+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/www.agencia.fapesp.br\/fotos\/2011\/45\/foto_dentro14751_1.jpg\" \/>\n<meta name=\"author\" content=\"inclusivenews2024\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"inclusivenews2024\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tempo estimado de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475\"},\"author\":{\"name\":\"inclusivenews2024\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#\\\/schema\\\/person\\\/ae4ec7087559b8692fb33b6fffd2273b\"},\"headline\":\"Novas s\u00edndromes gen\u00e9ticas\",\"datePublished\":\"2011-11-09T18:34:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475\"},\"wordCount\":779,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/www.agencia.fapesp.br\\\/fotos\\\/2011\\\/45\\\/foto_dentro14751_1.jpg\",\"articleSection\":[\"NOT\u00cdCIAS\",\"Sa\u00fade\"],\"inLanguage\":\"pt-PT\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475\",\"url\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475\",\"name\":\"Novas s\u00edndromes gen\u00e9ticas -\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/www.agencia.fapesp.br\\\/fotos\\\/2011\\\/45\\\/foto_dentro14751_1.jpg\",\"datePublished\":\"2011-11-09T18:34:30+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475#breadcrumb\"},\"inLanguage\":\"pt-PT\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-PT\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475#primaryimage\",\"url\":\"http:\\\/\\\/www.agencia.fapesp.br\\\/fotos\\\/2011\\\/45\\\/foto_dentro14751_1.jpg\",\"contentUrl\":\"http:\\\/\\\/www.agencia.fapesp.br\\\/fotos\\\/2011\\\/45\\\/foto_dentro14751_1.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/?p=21475#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"In\u00edcio\",\"item\":\"https:\\\/\\\/inclusivenews.com.br\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Novas s\u00edndromes gen\u00e9ticas\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#website\",\"url\":\"https:\\\/\\\/inclusivenews.com.br\\\/\",\"name\":\"Inclusive News\",\"description\":\"Inclusive News\",\"publisher\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/inclusivenews.com.br\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-PT\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#organization\",\"name\":\"Inclusive - inclus\u00e3o e cidadania\",\"url\":\"https:\\\/\\\/inclusivenews.com.br\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-PT\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/inclusivenews.com.br\\\/wp-content\\\/uploads\\\/2024\\\/03\\\/@grandesite.png\",\"contentUrl\":\"https:\\\/\\\/inclusivenews.com.br\\\/wp-content\\\/uploads\\\/2024\\\/03\\\/@grandesite.png\",\"width\":1080,\"height\":1080,\"caption\":\"Inclusive - inclus\u00e3o e cidadania\"},\"image\":{\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/agenciainclusive\\\/\",\"https:\\\/\\\/www.instagram.com\\\/newsinclusive\\\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/inclusivenews.com.br\\\/#\\\/schema\\\/person\\\/ae4ec7087559b8692fb33b6fffd2273b\",\"name\":\"inclusivenews2024\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-PT\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5a7ef84c66fa914f55bc4f7ce26cfa275a3b9a1c5568b907bd184fb4dde7b40?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5a7ef84c66fa914f55bc4f7ce26cfa275a3b9a1c5568b907bd184fb4dde7b40?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c5a7ef84c66fa914f55bc4f7ce26cfa275a3b9a1c5568b907bd184fb4dde7b40?s=96&d=mm&r=g\",\"caption\":\"inclusivenews2024\"},\"sameAs\":[\"https:\\\/\\\/inclusivenews.com.br\"],\"url\":\"https:\\\/\\\/inclusivenews.com.br\\\/?author=1\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Novas s\u00edndromes gen\u00e9ticas -","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/inclusivenews.com.br\/?p=21475","og_locale":"pt_PT","og_type":"article","og_title":"Novas s\u00edndromes gen\u00e9ticas -","og_description":"Nos \u00faltimos 14 anos, um novo grupo de doen\u00e7as heredit\u00e1rias raras come\u00e7ou a ser identificado em diferentes partes do mundo. S\u00e3o causadas por defici\u00eancias gen\u00e9ticas da imunidade inata e, se n\u00e3o forem diagnosticadas precocemente e tratadas de forma adequada, podem levar a complica\u00e7\u00f5es graves de sa\u00fade. Da Ag\u00eancia FAPESP.","og_url":"https:\/\/inclusivenews.com.br\/?p=21475","article_publisher":"https:\/\/www.facebook.com\/agenciainclusive\/","article_published_time":"2011-11-09T18:34:30+00:00","og_image":[{"url":"http:\/\/www.agencia.fapesp.br\/fotos\/2011\/45\/foto_dentro14751_1.jpg","type":"","width":"","height":""}],"author":"inclusivenews2024","twitter_card":"summary_large_image","twitter_misc":{"Escrito por":"inclusivenews2024","Tempo estimado de leitura":"4 minutos"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/inclusivenews.com.br\/?p=21475#article","isPartOf":{"@id":"https:\/\/inclusivenews.com.br\/?p=21475"},"author":{"name":"inclusivenews2024","@id":"https:\/\/inclusivenews.com.br\/#\/schema\/person\/ae4ec7087559b8692fb33b6fffd2273b"},"headline":"Novas s\u00edndromes gen\u00e9ticas","datePublished":"2011-11-09T18:34:30+00:00","mainEntityOfPage":{"@id":"https:\/\/inclusivenews.com.br\/?p=21475"},"wordCount":779,"commentCount":0,"publisher":{"@id":"https:\/\/inclusivenews.com.br\/#organization"},"image":{"@id":"https:\/\/inclusivenews.com.br\/?p=21475#primaryimage"},"thumbnailUrl":"http:\/\/www.agencia.fapesp.br\/fotos\/2011\/45\/foto_dentro14751_1.jpg","articleSection":["NOT\u00cdCIAS","Sa\u00fade"],"inLanguage":"pt-PT","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/inclusivenews.com.br\/?p=21475#respond"]}]},{"@type":"WebPage","@id":"https:\/\/inclusivenews.com.br\/?p=21475","url":"https:\/\/inclusivenews.com.br\/?p=21475","name":"Novas s\u00edndromes gen\u00e9ticas -","isPartOf":{"@id":"https:\/\/inclusivenews.com.br\/#website"},"primaryImageOfPage":{"@id":"https:\/\/inclusivenews.com.br\/?p=21475#primaryimage"},"image":{"@id":"https:\/\/inclusivenews.com.br\/?p=21475#primaryimage"},"thumbnailUrl":"http:\/\/www.agencia.fapesp.br\/fotos\/2011\/45\/foto_dentro14751_1.jpg","datePublished":"2011-11-09T18:34:30+00:00","breadcrumb":{"@id":"https:\/\/inclusivenews.com.br\/?p=21475#breadcrumb"},"inLanguage":"pt-PT","potentialAction":[{"@type":"ReadAction","target":["https:\/\/inclusivenews.com.br\/?p=21475"]}]},{"@type":"ImageObject","inLanguage":"pt-PT","@id":"https:\/\/inclusivenews.com.br\/?p=21475#primaryimage","url":"http:\/\/www.agencia.fapesp.br\/fotos\/2011\/45\/foto_dentro14751_1.jpg","contentUrl":"http:\/\/www.agencia.fapesp.br\/fotos\/2011\/45\/foto_dentro14751_1.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/inclusivenews.com.br\/?p=21475#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"In\u00edcio","item":"https:\/\/inclusivenews.com.br\/"},{"@type":"ListItem","position":2,"name":"Novas s\u00edndromes gen\u00e9ticas"}]},{"@type":"WebSite","@id":"https:\/\/inclusivenews.com.br\/#website","url":"https:\/\/inclusivenews.com.br\/","name":"Inclusive News","description":"Inclusive News","publisher":{"@id":"https:\/\/inclusivenews.com.br\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/inclusivenews.com.br\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-PT"},{"@type":"Organization","@id":"https:\/\/inclusivenews.com.br\/#organization","name":"Inclusive - inclus\u00e3o e cidadania","url":"https:\/\/inclusivenews.com.br\/","logo":{"@type":"ImageObject","inLanguage":"pt-PT","@id":"https:\/\/inclusivenews.com.br\/#\/schema\/logo\/image\/","url":"https:\/\/inclusivenews.com.br\/wp-content\/uploads\/2024\/03\/@grandesite.png","contentUrl":"https:\/\/inclusivenews.com.br\/wp-content\/uploads\/2024\/03\/@grandesite.png","width":1080,"height":1080,"caption":"Inclusive - inclus\u00e3o e cidadania"},"image":{"@id":"https:\/\/inclusivenews.com.br\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/agenciainclusive\/","https:\/\/www.instagram.com\/newsinclusive\/"]},{"@type":"Person","@id":"https:\/\/inclusivenews.com.br\/#\/schema\/person\/ae4ec7087559b8692fb33b6fffd2273b","name":"inclusivenews2024","image":{"@type":"ImageObject","inLanguage":"pt-PT","@id":"https:\/\/secure.gravatar.com\/avatar\/c5a7ef84c66fa914f55bc4f7ce26cfa275a3b9a1c5568b907bd184fb4dde7b40?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c5a7ef84c66fa914f55bc4f7ce26cfa275a3b9a1c5568b907bd184fb4dde7b40?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c5a7ef84c66fa914f55bc4f7ce26cfa275a3b9a1c5568b907bd184fb4dde7b40?s=96&d=mm&r=g","caption":"inclusivenews2024"},"sameAs":["https:\/\/inclusivenews.com.br"],"url":"https:\/\/inclusivenews.com.br\/?author=1"}]}},"_links":{"self":[{"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=\/wp\/v2\/posts\/21475","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=21475"}],"version-history":[{"count":0,"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=\/wp\/v2\/posts\/21475\/revisions"}],"wp:attachment":[{"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=21475"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=21475"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inclusivenews.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=21475"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}